Tratamiento actual y nuevas terapias contra la infección crónica por el virus de la Hepatitis B

Autores/as

  • Simón Gallo Echeverri Universidad de Antioquia
  • César Caraballo Cordovez Universidad de Antioquia, Facultad de Medicina
  • Mateo Orozco Marín Universidad de Antioquia
  • Octavio Germán Muñoz Hospital Pablo Tobón Uribe

DOI:

https://doi.org/10.22516/25007440.138

Palabras clave:

Virus de la Hepatitis B, Inmunoterapia, Antivirales, Hepatitis crónica, Cirrosis Hepática

Resumen

La infección crónica por el virus de la hepatitis B es un grave problema de salud pública a nivel mundial. Sus consecuencias llegan a ser mortales y el tratamiento actual no ofrece curación sino control de la enfermedad. Las principales limitantes para una cura son la dificultad para destruir el ADNccc del virus en el núcleo celular y la presencia de material genético viral integrado en el ADN de la célula hospedera. No obstante, hay múltiples frentes de investigación enfocados en encontrar una cura definitiva al potenciar la respuesta inmune del hospedero o al actuar directamente contra el virus y su ciclo de replicación. En este artículo se exponen los principales avances que se han realizado en este campo.

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Lenguajes:

es

Biografía del autor/a

Simón Gallo Echeverri, Universidad de Antioquia

Médico. Facultad de Medicina, Grupo de Gastrohepatología, Universidad de Antioquia.

César Caraballo Cordovez, Universidad de Antioquia, Facultad de Medicina

Médico,Facultad de Medicina, Universidad de Antioquia.

Mateo Orozco Marín, Universidad de Antioquia

Médico, Facultad de Medicina, Grupo de Gastrohepatología, Universidad de Antioquia.

Octavio Germán Muñoz, Hospital Pablo Tobón Uribe

Médico internista hepatólogo, Hospital Pablo Tobón Uribe. Grupo de Gastrohepatología, Universidad de Antioquia

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Publicado

2017-07-19

Cómo citar

Gallo Echeverri, S., Caraballo Cordovez, C., Orozco Marín, M., & Muñoz, O. G. (2017). Tratamiento actual y nuevas terapias contra la infección crónica por el virus de la Hepatitis B. Revista Colombiana De Gastroenterología, 32(2), 131–140. https://doi.org/10.22516/25007440.138

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