Eosinophilic colitis: a seldom suspected diagnosis
DOI:
https://doi.org/10.22516/25007440.376Keywords:
Colitis, eosinophilic, diarrhea, colonoscopy, biopsiesAbstract
Eosinophilic gastrointestinal disorders (EGID) are a group of disorders that compromise the gastrointestinal tract. The best known is eosinophilic esophagitis while eosinophilic colitis which was first reported in the literature in 1959 is less well-known. Eosinophilic colitis is characterized by functional digestive disorders, most importantly diarrhea. Although there are no clear diagnostic criteria, blood should be tested for eosinophils and biopsies taken by colonoscopies should be studied for histological findings of eosinophilic infiltration.
Eosinophilic colitis especially affects neonates and young adults and has been linked to genetic and allergic causes. Initial treatment consists of the suspension of allergens. Prednisolone is used to treat the disorder, and medications such as budesonide and immunomodulators can be used in refractory cases to achieve adequate response. We present an update.
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References
Kaiser R. Zur Kenntnis der allergischen affektionen des verdauungskanals vom standput des chirurgen aus. Archiv fur Klinische Chirugie. 1937;188:36–64.
Dunstone GH. A case of eosinophilic colitis. Br J Surg. 1959;46(199):474-6. https://doi.org/10.1002/bjs.18004619913
Rodríguez R, Bohórquez MA, González I, Torregroza G. Desórdenes eosinofílicos gastrointestinales (DEGI): presentación de dos casos. Rev Col Gastroenterol. 2007;22(2):138-148.
Talley NJ, Shorter RG, Phillips SF, Zinsmeister AR. Eosinophilic gastroenteritis: a clinicopathological study of patients with disease of the mucosa, muscle layer, and subserosal tissues. Gut. 1990;31(1):54-8. https://doi.org/10.1136/gut.31.1.54
Yan BM, Shaffer EA. Primary eosinophilic disorders of the gastrointestinal tract. Gut. 2009;58(5):721-32. https://doi.org/10.1136/gut.2008.165894
Okpara N, Aswad B, Baffy G. Eosinophilic colitis. World J Gastroenterol. 2009;15(24):2975–2979. https://doi.org/10.3748/wjg.15.2975
Guajardo JR, Plotnick LM, Fende JM, Collins MH, Putnam PE, Rothenberg ME. Eosinophil-associated gastrointestinal disorders: a world-wide-web based registry. J Pediatr. 2002;141(4):576-81. https://doi.org/10.1067/mpd.2002.127663
Dellon ES. Diagnosis and management of eosinophilic esophagitis. Clin Gastroenterol Hepatol. 2012;10(10):1066-78. https://doi.org/10.1016/j.cgh.2012.06.003
Arias Á, Pérez-Martínez I, Tenías JM, Lucendo AJ. Systematic review with meta-analysis: the incidence and prevalence of eosinophilic oesophagitis in children and adults in population-based studies. Aliment Pharmacol Ther. 2016;43(1):3-15. https://doi.org/10.1111/apt.13441
Mansoor E, Cooper GS. The 2010-2015 Prevalence of Eosinophilic Esophagitis in the USA: A Population-Based Study. Dig Dis Sci. 2016;61(10):2928-2934. https://doi.org/10.1007/s10620-016-4204-4
Rothenberg ME. Eosinophilic gastrointestinal disorders (EGID). J Allergy Clin Immunol. 2004;113(1):11-28. https://doi.org/10.1016/j.jaci.2003.10.047
Alfadda AA, Storr MA, Shaffer EA. Eosinophilic colitis: epidemiology, clinical features, and current management. Therap Adv Gastroenterol. 2011;4(5):301-9. https://doi.org/10.1177/1756283X10392443
Shaikh TP, Ansari S, Deolekar S, Mandhane N, Karandikar S. Eosinophilic colitis in 36 years old female: a case presentation with review of literature. 2015;1(3):172-176. https://doi.org/10.18203/issn.2454-2156.IntJSciRep20150354
Mansoor E, Saleh MA, Cooper GS. Prevalence of Eosinophilic Gastroenteritis and Colitis in a Population-Based Study, From 2012 to 2017. Clin Gastroenterol Hepatol. 2017;15(11):1733-1741. https://doi.org/10.1016/j.cgh.2017.05.050
Coste P, Campos C, Sauma J. Colitis eosinofílica: presentación endoscópica inusual. Endoscopia. 2016;28(4):166-169. https://doi.org/10.1016/j.endomx.2016.08.001
Prussin C. Eosinophilic gastroenteritis and related eosinophilic disorders. Gastroenterol Clin North Am. 2014;43(2):317-27. https://doi.org/10.1016/j.gtc.2014.02.013
Dionísio de Sousa IJ, Bonito N, Pais A, Gervásio H. Eosinophilic colitis. BMJ Case Rep. 2016;2016. pii: bcr2016214496. https://doi.org/10.1136/bcr-2016-214496
Alhmoud T, Hanson JA, Parasher G. Eosinophilic Gastroenteritis: An Underdiagnosed Condition. Dig Dis Sci. 2016;61(9):2585-92. https://doi.org/10.1007/s10620-016-4203-5
Gaertner WB, Macdonald JE, Kwaan MR, Shepela C, Madoff R, Jessurun J, et al. Eosinophilic colitis: university of Minnesota experience and literature review. Gastroenterol Res Pract. 2011;2011:857508. https://doi.org/10.1155/2011/857508
Hua S, Cook D, Walker MM, Talley NJ. Pharmacological treatment of eosinophilic gastrointestinal disorders. Expert Rev Clin Pharmacol. 2016;9(9):1195-209. https://doi.org/10.1080/17512433.2016.1190268
Mamachen A, Al-Hanayneh M, Bilal M, Merwat S, Hashmi A. Eosinophilic Colitis-”Not as rare”. Dig Liver Dis. 2017;49(7):826-828. http://dx.doi.org/10.1016/j.dld.2017.04.014
Lee JH, Park HY, Choe YH, Lee SK, Lee SI. The development of eosinophilic colitis after liver transplantation in children. Pediatr Transplant. 2007;11(5):518-23. https://doi.org/10.1111/j.1399-3046.2007.00693.x
Kefeli A, Yeniova AÖ, Başyiğit S, Güneş N. Eosinophilic colitis presenting with lower gastrointestinal bleeding: An uncommon entity with a rare presentation. Turk J Gastroenterol. 2015;26(5):440-1. https://doi.org/10.5152/tjg.2015.0180
Uppal V, Kreiger P, Kutsch E. Eosinophilic Gastroenteritis and Colitis: a Comprehensive Review. Clin Rev Allergy Immunol. 2016;50(2):175-88. https://doi.org/10.1007/s12016-015-8489-4
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