Primary gastric sarcoma: Case report and literature review

Authors

  • Helena Facundo Navia Instituto Nacional de Cancerologia
  • Juliana Rendon Instituto Nacional de Cancerología
  • Jorge Andres Mesa Instituto Nacional de Cancerología

DOI:

https://doi.org/10.22516/25007440.306

Keywords:

Leiomyosarcoma, gastric neoplasms, mesenchymal tumors

Abstract

Gastric cancer, a neoplastic pathology of undeniable importance, accounts for 90% of cases to adenocarcinoma. GIST lymphomas and gastrointestinal stromal tumors are the majority of the other 10%. However, non-GIST sarcomas remain a possible differential diagnosis to keep in mind and constitute a neoplastic pathology whose treatment is fundamentally surgical. Leiomyosarcoma represents less than 1% of malignant stomach tumors, and the available literature consists of case reports or case series. Because of its rarity, we present this clinical case and review the literature.

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Author Biographies

Helena Facundo Navia, Instituto Nacional de Cancerologia

Especialista en Cirugía Gastrointestinal y Endoscopia Digestiva. INC

Juliana Rendon, Instituto Nacional de Cancerología

Especialista en Cirugía Gastrointestinal y Endoscopia Digestiva. INC

Jorge Andres Mesa, Instituto Nacional de Cancerología

Especialista en patología oncologica. INC

References

McGrath PC, Neifeld JP, Lawrence W, Kay S, Horsley JS, Parker GA. Gastrointestinal sarcomas. Analysis of prognostic factors. Ann Surg. 1987;206(6):706-10. https://doi.org/10.1097/00000658-198712000-00004

Bassler A, Peters AG. Distinctions between gastric sarcoma and carcinoma with special reference to the infiltrating types of sarcoma. J Am Med Assoc. 1948;138(7):489-94. https://doi.org/10.1001/jama.1948.02900070021005

Peñaherrera V, Abarca J, Carrillo L. Leiomiosarcoma: reporte de un caso clínico. Rev Med. 2003;9(4):327-330.

Billings SD, Meisner LF, Cummings OW, Tejada E. Synovial sarcoma of the upper digestive tract: a report of two cases with demonstration of the X;18 translocation by fluorescence in situ hybridization. Mod Pathol. 2000;13(1):68-76. https://doi.org/10.1038/modpathol.3880011

Zhou W, Vasquez JC, O’Donnell MR, Paz BI. Clinical manifestations of gastrointestinal granulocytic sarcoma requiring surgical treatment. Am Surg. 2001;67(8):764-6.

Agaimy A, Gaumann A, Schroeder J, Dietmaier W, Hartmann A, Hofstaedter F, et al. Primary and metastatic high-grade pleomorphic sarcoma/malignant fibrous histiocytoma of the gastrointestinal tract: an approach to the differential diagnosis in a series of five cases with emphasis on myofibroblastic differentiation. Virchows Arch. 2007;451(5):949-57. https://doi.org/10.1007/s00428-007-0495-3

Kim HS, Kim S, Min YD, Kee KH, Hong R. Ewing’s Sarcoma of the Stomach; Rare Case of Ewing’s Sarcoma and Suggestion of New Treatment Strategy. J Gastric Cancer. 2012;12(4):258–261. http://dx.doi.org/10.5230/jgc.2012.12.4.258

Dougherty MJ, Compton C, Talbert M, Wood WC. Sarcomas of the gastrointestinal tract. Separation into favorable and unfavorable prognostic groups by mitotic count. Ann Surg. 1991;214(5):569–574. https://doi.org/10.1097/00000658-199111000-00006

Weledji EP, Enoworock G, Ngowe MN. Gastric leiomyosarcoma as a rare cause of gastric outlet obstruction and perforation: a case report. BMC Res Notes. 2014;7:479. https://doi.org/10.1186/1756-0500-7-479

Carson W, Karakousis C, Douglass H, Rao U, Palmer ML. Results of aggressive treatment of gastric sarcoma. Ann Surg Oncol. 1994;1(3):244-51. https://doi.org/10.1007/BF02303530

Lehnert T, Sinn HP, Wolf O. Diagnosis and surgical treatment of gastric sarcoma. Onkologie 1994;17:391–396. https://doi.org/10.1159/000218444

Koga H, Ochiai A, Nakanishi Y, Sasako M, Mizuno S, Kinoshita T, et al. Reevaluation of prognostic factors in gastric leiomyosarcoma. Am J Gastroenterol. 1995;90(8):1307-12.

Medina-Franco H, Eltoum IE, Urist MM, Heslin MJ. Primary gastrointestinal sarcomas. Am Surg. 2000;66(12):1171-5.

Farrugia G, Kim CH, Grant CS, Zinsmeister AR. Leiomyosarcoma of the stomach: determinants of long-term survival. Mayo Clin Proc. 1992;67(6):533-6. https://doi.org/10.1016/S0025-6196(12)60459-5

Yao KA, Talamonti MS, Langella RL, Schindler NM, Rao S, Small W, et al. Primary gastrointestinal sarcomas: analysis of prognostic factors and results of surgical management. Surgery. 2000;128(4):604-12. https://doi.org/10.1067/msy.2000.108056

Álvarez R, Arancibia A, Klaassen R, Gutiérrez G, González R, Molina H, et al. Tumores gástricos de estirpe muscular. Rev Chil Cir. 2003;55(5):470-475.

Beyrouti MI, Beyrouti R, Amar M, Frikha F, Abid M, Affes N, et al. Sarcomes gastriques. La Presse Médicale. 2008;37(3):e60-e66. https://doi.org/10.1016/j.lpm.2007.05.004

Fletcher CD. The evolving classification of soft tissue tumours - an update based on the new 2013 WHO classification. Histopathology. 2014;64(1):2-11. https://doi.org/10.1111/his.12267

ESMO/European Sarcoma Network Working Group. Soft tissue and visceral sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2014;25 Suppl 3:iii102-12. https://doi.org/10.1093/annonc/mdu254

Miettinen M. Smooth muscle tumors of soft tissue and non-uterine viscera: biology and prognosis. Mod Pathol. 2014;27 Suppl 1:S17-29. https://doi.org/10.1038/modpathol.2013.178

Baig MA. Evaluation of performance of various histological grading systems of soft tissue sarcomas and the prognosis (metastatic risk and survival rate). Int J Res Med Sci. 2015;3(9):2394-2401. https://doi.org/10.18203/2320-6012.ijrms20150637

Guillou L, Coindre JM, Bonichon F, Nguyen BB, Terrier P, Collin F, et al. Comparative study of the National Cancer Institute and French Federation of Cancer Centers Sarcoma Group grading systems in a population of 410 adult patients with soft tissue sarcoma. J Clin Oncol. 1997;15(1):350-62. https://doi.org/10.1200/JCO.1997.15.1.350

Khoshnevis J, Rakhshan A, Sobhiyeh MR, Gholizadeh B, Rahbari A, Adhami F, et al. Simultaneous gastric adenocarcinoma and gastrointestinal stromal tumor of the stomach: a case report. Iran J Cancer Prev. 2013;6(1):55–58.

Weng CH, Wang RC, Wu CC, Lin TH. Treatment of synchronous adenocarcinoma and lymphoma of the stomach: A case report. Mol Clin Oncol. 2016;5(6):783–785. https://doi.org/10.3892/mco.2016.1044

Published

2020-03-27

How to Cite

Facundo Navia, H., Rendon, J., & Mesa, J. A. (2020). Primary gastric sarcoma: Case report and literature review. Revista Colombiana De Gastroenterología, 35(1), 118–122. https://doi.org/10.22516/25007440.306

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Section

Case report

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