DOI: http://dx.doi.org/10.22516/25007440.327

Serología del virus de la hepatitis B: para múltiples escenarios, múltiples exámenes

William Alberto Otero Regino, Julián Parga, Johanna Gastelbondo

Resumen


El virus de la hepatitis B (VHB) tiene un gran impacto mundial. No obstante la disponibilidad de la vacuna, 2000 millones de personas se han infectado agudamente y, de ellos, 240 millones persisten crónicamente infectados. La infección tiene diferentes formas de presentación tales como infección aguda, infección crónica, infección oculta y reactivación cuando hay inmunosupresión. Así mismo, hay marcadores muy sensibles como el anticore, cuya positividad puede tener diversos significados. El recientemente descrito antígeno relacionado con el antígeno core es un marcador emergente que podría reemplazar al ácido desoxirribonucleico (ADN) viral. En la presente revisión se discuten los exámenes de laboratorio necesarios para el diagnóstico de los diferentes escenarios de la infección.


Palabras clave


virus B; infección oculta; anti-core; reactivación

Texto completo:

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Referencias


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